Response of bone marrow derived connective tissue progenitor cell morphology and proliferation on geometrically modulated microtextured substrates
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چکیده
منابع مشابه
Bone Marrow Derived Connective Tissue Progenitor Cell Responses on Microtextured Substrates with Controlled Mechanical Cues
Understanding and optimizing cell-substrate interactions is critical to the rational design of implant materials and tissue engineering scaffolds, particularly for bone healing applications [1]. Successful bone fracture healing depends upon having an osteoactive environment. The surface topography and mechanical stiffness of bone graft materials should allow transplanted cells to retain their f...
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Growth characteristics of human connective tissue progenitor (CTP) cells were investigated on smooth and textured substrates, which were produced using MEMS (microelectromechanical systems) fabrication technology. Human bone marrow derived cells were cultured for 9 days under conditions promoting osteoblastic differentiation on polydimethylsiloxane (PDMS) substrates comprising smooth (non-patte...
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چکیده ندارد.
15 صفحه اولIncrease of Palmitic Acid Concentration Impairs Endothelial Progenitor Cell and Bone Marrow–Derived Progenitor Cell Bioavailability
Metabolic profiling of plasma nonesterified fatty acids discovered that palmitic acid (PA), a natural peroxisome proliferator-activated receptor γ (PPARγ) ligand, is a reliable type 2 diabetes biomarker. We investigated whether and how PA diabetic (d-PA) concentrations affected endothelial progenitor cell (EPC) and bone marrow-derived hematopoietic cell (BM-HC) biology. PA physiologic (n-PA) an...
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Diabetic vascular pathology is largely attributable to impairments in tissue recovery from hypoxia. Circulating progenitor cells have been postulated to play a role in ischemic recovery, and deficiencies in these cells have been well described in diabetic patients. Here, we examine bone marrow-derived mesenchymal progenitor cells (BM-MPCs) that have previously been shown to be important for new...
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ژورنال
عنوان ژورنال: Biomedical Microdevices
سال: 2013
ISSN: 1387-2176,1572-8781
DOI: 10.1007/s10544-012-9727-7